CRISPR-based diagnostic SHERLOCK optimized for rapid use during viral outbreaks

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Researchers report a new tool that engineers the CRISPR-based diagnostic SHERLOCK for rapid outbreak response. The platform can now be used to detect viruses directly in clinical samples such as blood or saliva, eliminating a processing step that previously required a lab and professionally trained personnel. The updates to SHERLOCK enable clinicians to quickly and cheaply diagnose patient samples and track epidemics with limited equipment.



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